Endocrine Abstracts

Medical therapy of patients with acromegaly is an important addition to surgical treatment or an alternative to it when it is impossible to use the latter. Long-acting synthetic analogues of somatostatin (octreotide and lanreotide) act on the same subtypes of somatostatin receptors, but the drugs have been shown to differ in efficacy and tolerability.Objective: to achieve complete clinical and laboratory remission in patients with acromegaly, which did n...

Purpose: to assess the possibility of predicting the effectiveness of pharmacotherapy with metformin in patients with type 2 diabetes mellitus (DM2) depending on the single nucleotide polymorphism of the nitric oxide synthase gene.Materials and methods: 186 patients were examined, referred for planned hospitalization, the duration of DM2 was 6-8 years, the target level of glycated hemoglobin was 7.5%, the actual level was 8.3%. All patients were prescrib...

Relevance: There is a search for candidate genes that contribute to the progression of atherosclerosis in patients with diabetes mellitus. It has been suggested that the FABP2 Ala54Thr polymorphism may be associated with the risk of atherosclerosis.Objective: To evaluate the relationship between polymorphism of the intestinal fatty acid-binding protein (FABP2) gene Ala54Thr with peripheral atherosclerosis in patients with type 2 diabetes mellitus.<p ...

COVID-19 has a significant effect on the patient’s well-being even after the norm of laboratory parameters.The patients had cognitive blunting breathlessness, headache, fatigue, myalgia, weakness etc. The symptoms could last 3–12 months, from mild to severe, can lead to death.Purpose: To determine the significance of some biomarkers characterizing the condition of a patient with diabetes mellitus after undergoing covid.Ma...